Methanol Extracts Formulation of Tambora Leaves (Ageratum conyzoides L.), Sembalit Angin Leaves (Mussaendafrondosa L.) and Turmina Rhizome (Curcuma longa) as Candida albicans Antifungal
DOI:
https://doi.org/10.31958/js.v13i2.3473Keywords:
Combination formula, Ageratum conyzoides, Mussaendafrondosa, Curcuma longa, Candidaalbicans.Abstract
This study aimed to analyze the combination formula of Tambora leaves, Sembalit Angin leaves, and Turmeric Rhizomes using a 2: 1: 3 ratio, and determine its effect on the growth of Candida albicans. The growth indicator was measured based on the growth area of inhibition zone which marked by a clear zone between the outer sides of the paper disc. The growth activity was measured at the incubation period of 1x24 hours, 2x24 hours, and 3x24 hours. The observation data then were analyzed by oneway ANOVA statistical test continued with the Duncan test 1%. The results showed that the combination formula of bioherbal methanol extract of Tambora leaves, Sembalit Angin leaves, and turmeric rhizomes had a significant effect on the growth of Candida albicansat 1% significance, proven by the sig value. 0.00 <0.01. Therefore, the combination formula of bioherbal methanol extract of Tambora leaves, Sembalit Angin leaves, and Turmeric rhizomes can be recommended as a combination formula extract that can inhibit the growth of Candida albicans.
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Umar, U. Z. (2017). Analisis Vegetasi Angiospermae di Taman Wisata Wira Garden Lampung,. 61–62.
Yanti, N., Samingan, & Mudatsir. (2016). Uji Aktivitas Antifungi Ekstrak Etanol Gal Manjakani (Quercus Infectoria) terhadap Candida albicans. Angewandte Chemie International Edition, 1(1), 1–9.
Zuhud, E. A. M. (2009). Potensi Hutan Tropika Indonesia sebagai Penyangga Bahan Obat Alam untuk Kesehatan Bangsa. Jurnal Bahan Alam Indonesia, 6(6).
Ardiansyah, Hujjatusnaini, N., Amin, A. M., & Indahsari, L. I. Nu. (2021). Antibacterial Effectiveness of Methanol Extract Combination Formula 3:2:1 of Tambora Leaf (Ageratum conyzoides), Sembalit Angin Leaf (Mussaenda frondosa L), Turmeric Rhizome (Curcuma longa L) on the growth of Staphylococcos aureus. Sainstek : Jurnal Sains Dan Teknologi, 13(1), 1–6. https://doi.org/10.31958/JS.V13I1.3513
Astuti, H. (2015). Uji Aktivitas Antibakteri Ekstrak Etanol Dan Ekstrak Air Daun Bandotan ( Ageratum Conyzoides , L .) Terhadap Staphylococcus aureus Dan Escherichia coli. Majalah Farnaseutik, 11(1), 290–293.
Azizah, B., & Salamah, N. (2013). Standarisasi Parameter Non Spesifik Dan Perbandingan Kadar Kurkumin Ekstrak Etanol Dan Ekstrak Terpurifikasi Rimpang Kunyit. Pharmaciana, 3(1). https://doi.org/10.12928/pharmaciana.v3i1.416
Fuadi, T. M. (2017). Etnobotani Dan Identifikasi Tumbuhan Obat Bagi Ibu Pasca Melahirkan Di Desa Krueng Kluet Kecamatan Kluet Utara Aceh Selatan. Prosiding Biotik, 5(1), 280–288. https://jurnal.ar-raniry.ac.id/index.php/PBiotik/article/view/2161
Garvita, R. V. (2015). Pemanfaatan Tumbuhan Obat Secara Tradisional untuk Memperlancar Persalinan oleh Suku Dayak Meratus di Kalimantan Selatan. Warta Kebun Raya, 13(2), 51–58.
Gunadi, D., Oramahi, H. ., & Tavita, G. E. (2017). Studi tumbuhan obat pada etnis dayak di desa gerantung Kecamatan Monterado Kabupaten Bengkayang. Jurnal Hutan Lestari, 5(2), 425–436.
Halimatussa’diah, F., Fitriani, V. Y., & Rijai, L. (2014). Aktivitas Antioksidan Kombinasi Daun Cempedak (Artocarpus Champedan) Dan Daun Bandotan (Ageratum Conyzoides L) Fauziah. 2(5), 248–251.
Hariyati, T., Jekti, D. S. D., & Andayani, Y. (2015). Pengaruh Ekstrak Etanol Daun Jambu Air (Syzygium Aqueum) Terhadap Bakteri Isolat Klinis Titi. Journal Penelitian Pendidikan IPA, 1(2), 31–38.
Hidayat, D., & Hardiansyah, G. (2012). Studi Keanekaragaman Jenis Tumbuhan Obat di Kawasan IUPHHK PT . Sari Bumi Kusuma Camp Tontang Kabupaten Sintang. Jurnal Vokasi, 8, 61–68.
In-vitro, I. S., & Febia, A. (2020). Aktivitas Antifungi Ekstrak Metanol Daun Bandotan ( Ageratum conyzoides ) Terhadap Phytophthora sp. 9, 167–174.
Kusbiantoro, D., & Purwaningrum, Y. (2018). Pemanfaatan Kandungan Metabolit Sekunder Pada Tanaman Kunyit Dalam Mendukung Peningkatan Pendapatan Masyarakat Utilization Of Secondary Metabolite In The Turmeric Plant To Increase Community Income. 17(1), 544–549.
Mingga, M., Mingga, M., Oramahi, H. A., & Tavita, G. E. (2019). Pemanfaatan Tumbuhan Obat Oleh Masyarakat Di Desa Raba Kecamatan Menjalin Kabupaten Landak. JURNAL HUTAN LESTARI, 7(1), 97–105. https://doi.org/10.26418/jhl.v7i1.31005
Ngurah, I. G., Putra, P., & Estiasih, T. (2016). Potensi Hepatoprotektor Umbi-Umbian Lokal Inferior : Kajian Pustaka Hepatoprotective Potential of Local Inferior Tubers : A Review. 4(1), 436–442.
Ningsih, I. Y. (2016). Studi Etnofarmasi Penggunaan Tumbuhan Obat Oleh Suku Tengger Di Kabupaten Lumajang Dan Malang, Jawa Timur. Pharmachy, 13(01), 10.
Pangemanan, A., . F., & Budiarso, F. (2016). Uji daya hambat ekstrak rimpang kunyit (Curcuma longa) terhadap pertumbuhan bakteri Staphylococcus aureus dan Pseudomonas sp. Jurnal E-Biomedik, 4(1). https://doi.org/10.35790/ebm.4.1.2016.10840
Suraini, & Putri, N. (2018). EFEKTIFITAS ANTI JAMUR CAMPURAN REBUSAN JAHE (Zingiber officinale) DAN KUNYIT (Curcuma domestica) TERHADAP PERTUMBUHAN Candida albicans. 1(2), 73–77.
Umar, U. Z. (2017). Analisis Vegetasi Angiospermae di Taman Wisata Wira Garden Lampung,. 61–62.
Yanti, N., Samingan, & Mudatsir. (2016). Uji Aktivitas Antifungi Ekstrak Etanol Gal Manjakani (Quercus Infectoria) terhadap Candida albicans. Angewandte Chemie International Edition, 1(1), 1–9.
Zuhud, E. A. M. (2009). Potensi Hutan Tropika Indonesia sebagai Penyangga Bahan Obat Alam untuk Kesehatan Bangsa. Jurnal Bahan Alam Indonesia, 6(6).
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2021-12-31
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